Polycythemia Vera

Overview

Polycythemia vera (PV) is a rare blood disorder that causes the body to produce too many red blood cells, white blood cells, and platelets. This can lead to an increased risk of blood clots, which can be life-threatening if left untreated. PV is a type of myeloproliferative neoplasm (MPN), a group of diseases that affect the bone marrow’s ability to produce blood cells.

Symptoms

Common symptoms of polycythemia vera include:

  • Headaches or migraines
  • Dizziness or lightheadedness
  • Fatigue or weakness
  • Easy bruising or bleeding
  • Redness or warmth in the hands and feet
  • Itching or burning sensations in the skin
  • Weight loss or loss of appetite

Causes

The exact cause of polycythemia vera is not known, but it is thought to be related to:

  • Genetic mutations: PV is often associated with genetic mutations that affect the bone marrow’s ability to produce blood cells.
  • Family history: PV can run in families, suggesting a genetic link.
  • Environmental factors: Exposure to certain environmental toxins, such as radiation, may increase the risk of developing PV.

Diagnosis

Diagnosing polycythemia vera typically involves:

  • Blood tests to check for high levels of red blood cells, white blood cells, and platelets
  • Bone marrow biopsy to examine the bone marrow cells
  • Genetic testing to identify genetic mutations
  • Imaging tests, such as ultrasound or CT scans, to check for spleen enlargement

Treatment Options

Treatment for polycythemia vera usually focuses on reducing the risk of blood clots and managing symptoms. Our hospital offers a range of treatment options, including:

  • Phlebotomy (bloodletting) to reduce red blood cell count
  • Medications to reduce platelet count and prevent blood clots
  • Low-dose aspirin to prevent blood clots
  • Interferon therapy to slow down blood cell production
  • Stem cell transplantation in severe cases

Patient Success Stories

At Gertrude’s Children’s Hospital, we are committed to providing the best possible care for children with Polycythemia Vera. Here’s why families trust us:

“My daughter was diagnosed with polycythemia vera when she was just a teenager. The team at Gertrude's Children's Hospital was amazing - they worked with us to develop a personalized treatment plan that has helped her manage her symptoms and prevent complications.”

Rachelparent of a child with polycythemia vera

Living with Polycythemia Vera in children

Polycythemia vera is a specific type of myeloproliferative neoplasm that affects the bone marrow's ability to produce blood cells. Other blood disorders, such as essential thrombocythemia or primary myelofibrosis, affect different aspects of blood cell production.

There is no cure for polycythemia vera, but with proper treatment and management, most people with the condition can lead active and healthy lives.

You can reduce your risk of developing polycythemia vera by maintaining a healthy lifestyle, including a balanced diet, regular exercise, and not smoking.

Contact Us

If you suspect that your child may have polycythemia vera, we encourage you to schedule an appointment with our hematology clinic. Our team of experienced healthcare professionals is here to support you and your child every step of the way.

Contact us today to schedule an appointment or to learn more about our polycythemia vera treatment program.

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