Antiphospholipid Syndrome

Overview

Antiphospholipid syndrome (APS) is a rare autoimmune disorder that causes the body to produce antibodies that attack and damage the lining of blood vessels. This can lead to the formation of blood clots, which can be life-threatening if left untreated. APS can affect anyone, but it is more common in people with a family history of the condition.

Symptoms

Common symptoms of antiphospholipid syndrome include:

  • Recurring blood clots in the legs, lungs, or brain
  • Miscarriage or stillbirth
  • Stroke or transient ischemic attack (TIA)
  • Seizures or epilepsy
  • Headaches or migraines
  • Fatigue or weakness
  • Joint pain or swelling

Causes

The exact cause of antiphospholipid syndrome is not known, but it is thought to be related to:

  • Genetics: APS can run in families, suggesting a genetic link.
  • Autoimmune disorders: APS is often associated with other autoimmune disorders, such as lupus or rheumatoid arthritis.
  • Infections: Certain infections, such as Lyme disease, can trigger APS.
  • Hormonal changes: Hormonal changes during pregnancy or menstruation can trigger APS.

Diagnosis

Diagnosing antiphospholipid syndrome typically involves:

  • Blood tests to check for antiphospholipid antibodies
  • Imaging tests, such as ultrasound or CT scans, to check for blood clots
  • Physical exam and medical history
  • Genetic testing to check for genetic mutations

Treatment Options

Treatment for antiphospholipid syndrome usually involves:

  • Anticoagulation medications to prevent blood clots
  • Anti-inflammatory medications to reduce inflammation
  • Immunosuppressive medications to reduce the immune system’s attack on the body
  • Hormonal therapy to regulate hormonal imbalances
  • Lifestyle changes, such as quitting smoking and exercising regularly

Patient Success Stories

At Gertrude’s Children’s Hospital, we are committed to providing the best possible care for children with antiphospholipid syndrome. Here’s why families trust us:

“My daughter was diagnosed with antiphospholipid syndrome after a series of miscarriages. The team at Gertrude's Children's Hospital was amazing - they worked with us to develop a personalized treatment plan that helped her manage her symptoms and prevent further complications.”

Emilyparent of a child with antiphospholipid syndrome

Living with Antiphospholipid Syndrome in children

Antiphospholipid syndrome is a specific autoimmune disorder that causes the body to produce antibodies that attack and damage the lining of blood vessels. Other autoimmune disorders, such as lupus or rheumatoid arthritis, affect different parts of the body.

There is no cure for antiphospholipid syndrome, but with proper treatment and management, most people with the condition can lead active and healthy lives.

You can reduce your risk of developing antiphospholipid syndrome by maintaining a healthy lifestyle, including a balanced diet, regular exercise, and not smoking.

Contact Us

If you suspect that your child may have antiphospholipid syndrome, we encourage you to schedule an appointment with our hematology clinic. Our team of experienced healthcare professionals is here to support you and your child every step of the way.

Contact us today to schedule an appointment or to learn more about our antiphospholipid syndrome treatment program.

Contact us today to schedule an appointment or to learn more about our Anemia of Chronic Disease treatment program.

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