Immune Thrombocytopenic Purpura (ITP)

Overview

Immune Thrombocytopenic Purpura (ITP) is a rare bleeding disorder that affects the blood’s ability to clot. It happens when the immune system mistakenly attacks and destroys platelets, which are the cells that help the blood to clot. This can cause problems with bleeding and bruising.

Symptoms

Common symptoms of ITP include:

Easy bruising or bleeding
Petechiae (small red or purple spots on the skin)
Purpura (larger purple spots on the skin)
Nosebleeds or bleeding gums
Heavy menstrual bleeding in girls and women
Fatigue or weakness

Causes

The exact cause of ITP is not known, but it’s thought to be related to an abnormal immune response. In people with ITP, the immune system produces antibodies that attack and destroy platelets. This can be triggered by a number of factors, including:

Viral infections, such as the flu or a cold
Bacterial infections, such as strep throat
Certain medications, such as antibiotics or anticonvulsants
Hormonal changes, such as those that occur during pregnancy or menstruation

Diagnosis

Diagnosing ITP typically involves a combination of the following tests:

Complete Blood Count (CBC) to check for low platelet count
Blood smear to look for abnormal platelets
Bone marrow biopsy to rule out other bleeding disorders
Tests to check for antibodies against platelets

Treatment Options

Treatment for ITP depends on the severity of the condition and the individual’s overall health. Our hospital offers a range of innovative and effective treatment options, including:

Medications to increase platelet count, such as corticosteroids or immunoglobulin
Platelet transfusions to replace destroyed platelets
Splenectomy (removal of the spleen) to reduce the destruction of platelets
Rituximab, a medication that targets the immune system’s abnormal response

Why Choose Us

At Gertrude’s Children’s Hospital, our team of experienced and compassionate hematologists and other healthcare professionals specialize in the diagnosis and treatment of ITP in children. Our hospital offers:

State-of-the-art facilities and equipment, including a pediatric hematology unit
A multidisciplinary team approach to care, including hematologists, oncologists, and other specialists
Innovative and effective treatment options, including rituximab and splenectomy
A supportive and nurturing environment that promotes healing and growth

Patient Success Stories

At Gertrude’s Children’s Hospital, we are committed to providing the best possible care for children with ITP. Here’s why families trust us:

“Our child was diagnosed with ITP at a young age, and we were worried about the risks of bleeding and bruising. But the team at Gertrude's Children's Hospital was amazing - they worked with us to develop a personalized treatment plan that helped our child manage the condition and live a normal life.”
Sarahparent of a child with ITP

Frequently Asked Questions (FAQs)

ITP is a specific type of bleeding disorder that is caused by an abnormal immune response. Other bleeding disorders, such as hemophilia, are caused by different factors.

Treatment for ITP in children typically involves a combination of medications and other therapies, such as platelet transfusions and splenectomy.

With proper treatment, many children with ITP can achieve long-term remission and recovery. However, some children may experience ongoing symptoms and require ongoing treatment.

Contact Us

If you suspect that your child may have ITP, we encourage you to schedule an appointment with our pediatric hematology team. Our team of experienced healthcare professionals is here to support you and your child every step of the way.

Contact us today to schedule an appointment or to learn more about our aplastic anemia treatment program.